CONFORMATIONAL MODULATION OF INFLUENZA VIRUS HEMAGGLUTININ: CHARACTERIZATION AND IN VIVO EFFICACY OF MONOMERIC FORM

Conformational modulation of influenza virus hemagglutinin: characterization and in vivo efficacy of monomeric form

Abstract Mutational changes that mostly occur at the head region of hemagglutinin (HA) lead to the emergence of new epidemic influenza viruses, whereas HA antigens have been modified to generate broadly neutralizing antibodies toward highly conserved epitopes in the HA stem.Interestingly, a recent analysis of serum antibody repertoires showed that

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Archaeology of Modern Conflict and Heritage Legislation in Lithuania during Thirty Years of Restored Independence

After the Lithuanian National Revival in 1988 and the restoration of independence in 1990, the public on their own initiative searched for the remains of fallen anti-Soviet Lithuanian partisans (1944-1953), excavating the burial sites of partisan remains, their bunkers and dugouts.Such excavations prompted the need to sweers island for sale establi

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ERAP1 Controls the Interaction of the Inhibitory Receptor KIR3DL1 With HLA-B51:01 by Affecting Natural Killer Cell Function

The endoplasmic reticulum aminopeptidase ERAP1 regulates innate and adaptive immune responses by trimming peptides for presentation by major histocompatibility complex (MHC) class I molecules.Previously, we have shown that genetic or pharmacological inhibition of ERAP1 on murine and human tumor cell lines perturbs the engagement of NK cell inhibito

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